Make the Big Mac sauce: In a small bowl, combine the mayonnaise, ketchup, chopped dill pickles, and pickle juice. Stir well until everything is mixed together. Set aside in the fridge while you cook the beef. This lets the flavors meld together!
Cook the beef: Heat the oil in a large skillet over medium-high heat. Add the white onion and sauté for 2-3 minutes until it starts to soften.
Add the ground beef: Add the lean ground beef to the skillet, breaking it up with a wooden spoon or spatula. Cook for 5-7 minutes, stirring occasionally, until the beef is browned and cooked through.
Season: Add the mustard, garlic powder, and onion powder to the beef. Stir well to combine.
Add the cheese: Reduce heat to low. Sprinkle the shredded cheddar cheese evenly over the beef. Cover the skillet with a lid and let it sit for a few minutes until the cheese is melted and gooey.
Assemble: Remove from heat. Drizzle the Big Mac sauce over the cheesy beef (use as much or as little as you like — you can always save some for dipping!).
Add fresh toppings: Top with shredded iceberg lettuce, dill pickles and onions.
Serve: Serve immediately over fries, rice, or just by itself! You can also let everyone build their own bowls buffet-style with all the toppings on the side.